On the downside, larger companies tend to have a one-size-fits-all attitude to employees. There will be lots of rules and regulations and some people find this stifling.

If you like variety and hate bureaucracy then a small company could be right for you. You will have a more personal relationship with the boss and with your manager and this will allow them to be more flexible with the rules. A lot of small companies have a family-like atmosphere and a relaxed working style.